Laboratory of Neural Circuits & Behavior

Laboratory of Neural Circuits & Behavior


Gaunt, J.R., Zainolabidin, N., Yip, A.K.K., Tan, J.M., Low, A.Y.T., Chen, A.I.* and Ch'ng T.H.* (2023). Cytokine enrichment in deep cerebellar nuclei is contributed by multiple glial populations and linked to reduced amyloid plaque pathology. J Neuroinflammation 20, 269. *corresponding authors pdf

Low, A.Y.T., Goldstein, N., Gaunt, J., Huang, K.P., Zainolabidin, N., Yip, A.K.K., Carty, J., Choi, J., Ho, H.S.T., Lenherr, C., Balter, N., Miller, A., Azim, E., Sessions, O., Ch’ng, T.H., Bruce, A., Martin, L., Halko, M., Brady, R., Holsen, L., Alhadeff, A., Chen, A.I.*, Betley, J.N.* (2021). Reverse-translational identification of a cerebellar satiation network. Nature 600, 269-273. *corresponding authors pdf news and views

Thanawalla, A.R., Chen, A.I.*, Azim, E*. (2020). The cerebellar nuclei and dexterous limb movements. Neuroscience 450, 168-183. *corresponding authors pdf

Kamath, S., Chen, A.I. (2019). Myocyte enhancer factor 2c regulates dendritic complexity and connectivity of cerebellar Purkinje cells. Molecular Neurobiology 56, 4102-19. pdf

Tan, S., Xiao, Y., Chen, A.I., Soon, T.W., Je, H.S. (2018). Postnatal TrkB ablation in corticolimbic interneurons induces social dominance in male mice. Proceedings of the National Academy of Sciences 115, E9909-9915. pdf

Low, A.Y.T., Thanawalla, A.R., Yip, A.K.K., Kim, J., Wong, K.L.L., Tantra, M., Augustine, G.J., Chen, A.I. (2018). Precision of discrete and rhythmic forelimb movements requires a distinct neuronal subpopulation in the interposed anterior nucleus. Cell Reports 22, 2322-33. pdf

Tantra, M., Guo, L., Kim, J., Zainolabidin, N., Augustine, G.J., Eulenburg, V., Chen, A.I. (2018). Conditional deletion of Cadherin-13 perturbs Golgi cells and disrupts cognitive and social behaviors. Genes, Brain and Behavior 15, e12466. pdf

Zainolabidin, N., Kamath, S.P., Thanawalla, A.R., Chen, A.I. (2017). Distinct activities of Tfap2A and Tfap2B in the specification of GABAergic interneurons in the developing cerebellum. Frontiers in Molecular Neuroscience 10, 281. pdf

Chen, A.I.*, Zang, K., Masliah, E., Reichardt, L.F. (2016). Glutamatergic axon-derived BDNF controls GABAergic synaptic differentiation in the cerebellum. Scientific Report 6, 20201. *corresponding author pdf

Chen, A.I., Nguyen, C.N., Copenhagen, D.R., Badurek, S., Minichiello, L., Ranscht, B. Reichardt, L.F. (2011). TrkB controls the assembly and maintenance of GABAergic synapses in the cerebellar cortex.  The Journal of Neuroscience. 31, 2769-80. pdf

Chen, A.I., de Nooij, J.N., Jessell, T.M. (2006). Graded activity of transcription factor Runx3 specifies the laminar termination pattern of sensory axons in the developing spinal cord.  Neuron 49, 395-408. pdf

Novitch, B.G., Chen, A.I., Jessell, T.M. (2001). Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH repressor Olig2. Neuron 31, 1-17. pdf

Chen, A., Tang, Y., Zhuo, Y., Wang, Q., Pahk, A., Field, J. (2001). Ras activation of  Pak protein kinases. Methods in Enzymology. Regulators and Effectors of Small GTPases 333, 55-61. pdf

Tang, Y., Zhou, H., Chen, A., Pittman, R.N., Field, J. (2000). The Akt proto-oncogene links Ras to Pak and cell survival. Journal of Biological Chemistry 275, 9106-09. pdf

Tang, Y., Chen, A., Zhuo, Y., Wang, Q., Pahk, A., Field, J. (1999). Pak protein kinases as mediators of Ras signaling and cell transformation. A place for Pak on the Ras MAP: More than just another JNK bond. Gene Therapy and Molecular Biology 4, 411-416. pdf